Alcohol And Gastric Bypass Surgery Might Turn Out To Be A Dangerous Mix

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In 2005, Wnt-3 antibodies were chosen by D.C Lie et al to demonstrate that adult astrocytes released Wnt-3 in vivo along with vitro to stimulate neurogenesis. However, the actual mechanism of action and downstream genetic targets remained obscure. In 2009, independent studies led by T. Kuwabara and Z. Gao viewed the role of the proneural transcription factor NeuroD1, which is considered required for granule neuron production inside hippocampus during development. In 2004, J. Hsieh et al used progenitor cells isolated through the rat hippocampus, to demonstrate neuronal differentiation following NeuroD1 overexpression.

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